Understanding Alzheimer’s disease may mean learning more about the liver

(STUDY FINDS) – The majority of research dedicated to understanding and treating Alzheimer’s disease has been, understandably, focused on the brain. Now, however, new research out of Spain conducted at the Autonomous University of Barcelona is lending further credence to the hypothesis that oxidative stress and inflammation, in combination with the natural aging process, may play an important role in the development of dementia. According to the theory, the liver could be a key, yet overlooked, organ in the development and prognosis of Alzheimer’s disease, the most common form of dementia.

The liver is an integral bodily organ, responsible for regulating metabolism and supporting the immune system.

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A research team from the UAB Institut de Neurociències led by Professor Lydia Giménez-Llort from the UAB Department of Psychiatry and Legal Medicine, in collaboration with Professor Josep Reig-Vilallonga from the UAB Department of Morphological Sciences, investigated this hypothesis by comparing Alzheimer’s disease mice models with a group of control rodents of the same advanced age and sex.

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